In particular, I will focus on the role for the antagonism between various transcription factors and epigenetic enzymes in controlling the commitment of muscle stem cells towards alternate cell fates. (inmg.fr)
By identifying the epigenetic determinants and the responsible epigenetic enzymes controlling these different forms of cardiac myocyte hypertrophy, as well as how the epigenetic modifiers are themselves regulated by micoRNAs, we provide a potential strategy for epigenetic therapy for adverse cardiac remodelling. (sciencedaily.com)
The researchers next used a cutting - edge technique that encourages epigenetic enzymes to bind to DNA, allowing them to identify all the genes inhibited by HDAC5. (sciencedaily.com)