A surgeon injected one eye of each patient with a solution containing a harmless virus that ferried a good copy of RPE65 into retinal cells. (sciencemag.org)
The drugs are most effective when given in the early courses of the disease, or prophylactically in the normal eye of a patient who has developed glaucoma. (cvm.ncsu.edu)
The researchers were concerned that re-administering the vector in the untreated eye of the patients might stimulate an inflammatory response that could reduce the initial benefits in the untreated eye. (rpbusa.org)