Rodriguez had already observed how HDL pulls cholesterol out of foam cells, which are found in the plaque that accumulates on blood vessel walls in people with atherosclerosis. (discovermagazine.com)
«We would take foam cell [models] and make them chock full of cholesterol, put HDL outside the cell, and see how well cholesterol was moving out of the cell — the more HDL the better,» Rodriguez recalls. (discovermagazine.com)
The only other one that comes to mind is the SENS foundation's development of an enzyme for removing oxidized cholesterol from foam cells. (fightaging.org)