Once the neural tube is closed, the protective effects of folic acid supplementation wear off. (mindbodygreen.com)
There is still far more evidence in favor of using folic acid supplementation than evidence against it, but these findings do show that keeping within the recommended limits may be a good idea. (verywellfamily.com)
This is because folic acid supplementation this high can trigger B12 deficiency symptoms. (robdaquila.com)