Phrases with «gene knockout»

"Gene knockout" refers to a scientific technique where a specific gene is intentionally deactivated or removed from an organism's DNA. This allows researchers to study the effects of that gene's absence and understand its role in the organism's traits or functions. Full definition

Sentences with «gene knockout»

  • These studies from the Capecchi and Smithies laboratories provided one of the essential ingredients for constructing gene knockouts in mice, the ability to target genes in cultured animal cells. (laskerfoundation.org)
  • In this study, by using a systemic mtEF4 gene knockout mouse model, researchers found that mtEF4 knockout damages the oxidative phosphorylation function in germ cells of male mice, thus causing male sterility. (sciencedaily.com)
  • Meehan et al., (2017) Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium. (infrafrontier.eu)
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