Anti-sense oligonucleotides or ASOs are one type of gene silencing drug, made from a DNA - like chemical. (en.hdbuzz.net)
It has also been suggested that methylation is not the initial event in triggering gene silencing in cancer; rather, the methylation of the promoter CpG islands is a consequence of prior gene inactivation, and it is a mechanism for locking the chromatin in a repressed state (5, 13, 37). (cancerres.aacrjournals.org)
«These particles, microRNA based SNAs, could also potentially be used for gene silencing in other cancers and diseases of genetic origin.» (sciencedaily.com)