In the last decade the identification of genetic drivers of melanoma cell which regulate proliferation and survival - such as BRAF and other activators of the MAP - kinase pathway - along with the recent development of immunotherapy has taken away in many cases the invasive treatment of melanoma as an option. (jbiomed.com)
Scientists from the Icahn School of Medicine at Mount Sinai have developed and publicly released new data analysis software that could help genomics researchers identify genetic drivers of disease with greater efficiency and accuracy. (sciencedaily.com)
If metastatic cancers are most often made up of cells with different genetic drivers, perhaps researchers should be targeting the primary tumor with multiple drugs to contain the cancer. (sciencedaily.com)