Above two sets of experiments indicate that inhibition of either ERK1 / 2 or AKT activation prior to 2.0 or 3.0 Gy of radiation moderately but equally sensitized B16F10 cells to radiation - induced cell death while inhibition of JNK enhanced radiation - induced cell death at relatively low level. (wjon.org)
Dosage of 3 Gy per fraction are well tolerated and do not appear to be associated with significant delayed reactions such as brain necrosis that can be seen at higher dosages. (veterinarycancer.com)
Inhibition of ERK1 / 2 and AKT equally enhanced radio - sensitivity of B16F10 cells exposed to 2.0 and 3.0 Gy electron beam radiation (wjon.org)