Phrases with «human amyloid»

The phrase "human amyloid" refers to a substance called amyloid that can accumulate in the body, specifically in the brain, nerves, or other organs of humans. This accumulation can lead to certain diseases, such as Alzheimer's disease or systemic amyloidosis, which can cause problems with memory, thinking, and overall body functions. Amyloid is a type of protein that clumps together abnormally, and it is important to understand it to find ways to prevent or treat these diseases. Full definition

Sentences with «human amyloid»

  • Specifically, rodents genetically modified to express human amyloid precursor protein (hAPP), which can lead to the debilitating plaques that form in the brains of Alzheimer's patients, seem to struggle to find the hidden platform relative to their healthy peers. (sciencemag.org)
  • We compared transgenic mice that express human amyloid precursor protein (hAPP) and patients with mild cognitive impairment due to Alzheimer's disease (MCI - AD) to evaluate the sensitivity of performance measures in detecting deficits. (jci.org)
  • Increasing EphB2 levels in neurons of mice engineered to produce high levels of human amyloid proteins in the brain prevented their neurotransmission deficits, memory problems and behavioral abnormalities. (gladstone.org)
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