The researchers are now comparing these strains with human liver cells. (newscientist.com)
Often, their behavior does not reflect their biological function within an entire organ or organism, which, for example, turns studying human liver cells into a big challenge. (salk.edu)
The authors noticed the gene expression landscape in the generated liver buds — such as precisely where and when genes express themselves — did not completely match natural human liver cells. (sciencedaily.com)