With the advent of genome engineering, scientists are now introducing hundreds of different human mutations in other species to study their effects and develop new drugs. (sciencedaily.com)
Then they counted the number of mtDNA differences between individuals and used the modern human mutation rate to estimate how long it might have taken those mutations to appear. (sciencemag.org)
Human mutations affecting this subgroup of ADAMTS / ADAMTSL proteins phenocopy all or several aspects of genetic disorders caused by mutations in the fibrillin - 1 gene itself, suggesting a functional relationship. (lerner.ccf.org)