Without overt evidence of other illnesses, though, most cases of hyperkeratosis require skin biopsies that are then evaluated along with your dog's breed information, history and physical findings. (pethealthnetwork.com)
Idiopathic digital hyperkeratosis usually occurs in dogs older than 10. (dogcare.dailypuppy.com)
Dogs can also suffer from a condition called Hyperkeratosis of the foot pads (hard pad disease) and the nose, which is a thickening of the skin in those areas. (dog-health-handbook.com)