To test the role of innate immune response in the mouse model of ALS, the researchers focused on Toll - like receptors (TLR), which are important sensors for innate immunity. (sciencedaily.com)
In 2010, we formally demonstrated ADE by developing a mouse mode of ADE - mediated disease, and we began to dissect the contribution of humoral vs. cellular immune components in dengue vaccine - mediated protection using model vaccine candidates as tools to probe the mechanisms by which the vaccine - induced immune responses in mice contribute to protection vs. ADE. (lji.org)
That increase inhibited the ability of regulatory T cells to suppress the Th2 immune response in mice. (sciencedaily.com)