The phrase "immunocompetent mice" refers to mice that have a fully functional immune system, which means their bodies are capable of fighting off infections and diseases effectively. Full definition
This study focuses on the engraftment of HPCs in immunocompetent mice and proposes a strategy that could exploit available human ES cell lines to improve organ transplantation. (journals.plos.org)
To sidestep the shortcomings of currently used cancer models, the Salk team harnessed the power of lentiviral vectors to infect nondividing as well as dividing cells and ferry activated oncogenes into a small number of cells in adult, fully immunocompetent mice. (salk.edu)
Although a number of groups have already looked at the engraftment of ES - derived HPCs in Rag2 − / − γc − / − mice, there are no reports on HPC engraftment in either syngeneic or allogenic immunocompetent mice. (journals.plos.org)