Lee says the research team will measure the amount of methylation in patients» cells when they begin their treatment and the presence of genes associated with irinotecan resistance, among other possible biomarkers. (sciencedaily.com)
The UCLA research team designed a nanoparticle comprised of a hollow silica core surrounded by a lipid bilayer to enhance the delivery of irinotecan in an animal model with pancreatic cancer. (sciencedaily.com)
A new animal model of intestinal mucositis induced by the combination of irinotecan and 5 - fluorouracil in mice. (cambridge.org)