The word "irreversible" means that something cannot be undone or changed back to the way it was before. It is permanent and cannot be reversed. Full definition
Always take the time to get the right medication from your veterinarian to prevent causing irreversible damage to your dog's system. (smartdogowners.com)
The prognosis becomes «grave» if pancreatic juices spread to adjacent organs of the pancreas; which cause irreversible damage. (dog-health-handbook.com)
Any eye condition can be alarming and, while many are not true emergencies, a significant delay in treatment can result in irreversible changes rapidly in some situations. (veterinaryvision.com)