The phrase "irreversible loss" refers to a loss or damage that cannot be undone or recovered. It is a permanent and unchangeable kind of loss. Full definition
They raised more fundamental questions about how to deal with irreversible losses from climate change. (newsecuritybeat.org)
Given the enormous consequences and irreversible losses from global warming should the worst projections play out, the time for improving the flow of information on this subject is clearly now. (dotearth.blogs.nytimes.com)
However, there's plenty of action, humor and heart — and some genuinely effective dramatic moments in which familiar and beloved characters experience real, seemingly irreversible losses. (metacritic.com)