Human islet amyloid polypeptide expression in COS - 1 cells. (academic.oup.com)
People with Type 2 diabetes have an excess of a protein called islet amyloid polypeptide, or IAPP, and the accumulation of this protein is linked to the loss of insulin - producing pancreatic beta cells. (sciencedaily.com)
Fibrils immunoreactive for islet amyloid polypeptide are found in macrophages associated with amyloid, suggesting that deposits can be phagocytosed. (sens.org)