It inhibits two tyrosine kinase enzymes called Jak1 and Jak2, which rev up production of immune cells. (sciencemag.org)
One option is an MEK inhibitor, which inhibits the mitogen - activated protein kinase enzymes used to therapeutically affect the MAPK pathway that is often overactive in cancers. (sciencedaily.com)
Metformin, which acts on the AMP kinase enzyme, lowers blood sugar and improves insulin sensitivity, thus altering insulin production. (discovermagazine.com)