Scanning electron micrograph of the coronary microvasculature of a mouse that has been treated with a small molecule tyrosine kinase inhibitor of platelet - derived growth factor receptor beta. (mdanderson.ilabsolutions.com)
A number of kinase inhibitors in the clinic for the therapy of lung cancer have more than a single protein target. (iaslc.org)
In this theory it is explained that cutaneous melanoma occurs mainly due to DNA damage involving the region of cyclin dependent kinase inhibitor 2A gene (CDKN2A), as a result of exposure to excessive amounts of ultraviolet (UV) radiation from sunburn in early stages of life [25]. (jbiomed.com)