We evaluated four independent library preparation methods and two sequencing platforms (9)(table S1) for our first batch of 15 inactivated EVD samples from 12 patients. (science.sciencemag.org)
The TMWG kit incorporates Cambridge Epigenetix's TrueMethyl oxidative bisulfite (oxBS) technology, which allows researchers to accurately quantify different DNA modifications at single - base resolution, as well as proprietary library preparation methods designed to overcome the limitations of traditional bisulfite library construction, and to improve the yield and quality of epigenetic data. (sciencemag.org)