Dosing of mebendazole of 30 - 87 mg / kg / day in humans resulted in plasma levels of 120 -218 nM (260 nM for continuous administration) with coefficients of variation ranging from 27 to 72 %. (oncm.org)
In detail, agents such as mebendazole and flubendazole induce the loss of cytoplasmic microtubules of the tegumental and intestinal cells of the helminths, and this is followed by loss of transport of secretory vesicles, a decreased glucose uptake and an increased utilization of stored glycogen [12]. (oncm.org)
The anthelmintic drug mebendazole inhibits growth, migration and invasion in gastric cancer cell model. (oncm.org)