Takagi was approached by Prof. Atsuko Yamashita at Okayama University who had been studying the T1r2 - T1r3 heterodimer of medaka fish for years. (sciencedaily.com)
«We started by looking for proteins that cause ER stress during the development of medaka fish embryos, which are known to have the same ten transducers,» explains first author Ishikawa. (sciencedaily.com)
Germ cells, irrespective of the sexual fate (to become sperm or eggs), have the potential to feminize the body in medaka. (sciencedaily.com)