Methods: The PNNL team applied global proteome profiling in combination with UCSD - developed phosphoproteomics approaches to understand signal organization in migrating cells. (pnnl.gov)
These are some of the fastest migrating cells in the human body, and they are the first responders at damaged locations or areas of infection and begin the process of healing. (scientificamerican.com)
This process requires a fundamental change in the character of cells within the primary tumor, insofar as members of a localized cell mass must be converted into actively migrating cells that invade into the surrounding tissue and blood vessels, and finally settle in distant tissues. (sciencedaily.com)