The LITE system can now be applied to unraveling the genetic and epigenetic players in normal biological processes and disease states. (blog.addgene.org)
Carcinogens may cause cancer by altering cellular metabolism or damaging DNA directly in cells, which interferes with normal biological processes. (sciencedaily.com)
A potential drug target would have to be found within the cancer - causing pathways activated by Rac1b, since the enzyme is difficult to target because it is involved in many normal biological processes, Dr. Radisky says. (sciencedaily.com)