We show that mutations and structural variations outside of the coding genome can interfere with normal gene regulation by disrupting the regulatory landscape. (ashg.org)
One approach is to deliver a working copy of the entire gene within a virus, but this method can disrupt normal genes. (sciencemag.org)
However, the insertion of this viral genetic material (and later, pieces of viral genetic material) can alter the cat's normal genes in such a manner as to cause disease later in life. (2ndchance.info)