Both the knockout and normal phenotype data will be made available through the KOMP2 data coordination center so that researchers who acquire and study the knockout mice can compare various phenotypes. (genome.gov)
The hTNFR1KI mice have normal phenotype and can be used in combination to other genetic models (e.g. Tg197hTNFR1KI) or with a variety of induced disease models in order to test the efficacy of anti-human TNFR1 therapeutics. (biomedcode.com)
Butyrate is a preferred substrate for colonocytes and appears to promote a normal phenotype in these cells. (freetheanimal.com)