To implement therapy, he separated cd4 cells from the rest of the blood and conducted zinc finger nuclease editing in the lab to delete CCR5. (discovermagazine.com)
CRISPR - Cas9 nucleases consist of the Cas9 bacterial enzyme and a short, 20 - nucleotide RNA molecule that matches the target DNA sequence. (sciencedaily.com)
Science magazine heralded these transcription activator - like effector nuclease proteins, known as TALENS, as a major scientific breakthrough in 2012, nicknaming them «genomic cruise missiles» for their ability to allow researchers to target specific locations with great efficiency. (vtnews.vt.edu)