The phrase "nucleotide level" refers to the smallest building blocks of DNA or RNA molecules. These are tiny structures that combine to form genes and carry important information for cell functions. Full definition
The study used whole - exome sequencing to characterize genetic alterations that occur at the single nucleotide level for all genes in 25 cell lines commonly used as models of bladder cancer. (sciencedaily.com)
Thus, when nucleotide levels are low and c - MYC concentration drops, transcription will be down - regulated as well. (sciencedaily.com)
Resolving nucleotide modifications at the single molecule, single nucleotide level, especially when integrated with other single molecule - or single cell - level data, such as RNA and protein expression, will help resolve regulatory relationships that govern higher order phenotypes such as drug resistance» said Eric Schadt, Ph.D., founding director of the Icahn Institute and professor of genomics at the Icahn School of Medicine at Mount Sinai. (sciencedaily.com)