Histopathological studies of occipital bone development are needed in order to compare the CKCS to other breeds of dog. (journals.plos.org)
Caudal occipital malformation syndrome is a genetic deformation of the mesoderm of caudal occipital bone causing cerebellar compression and herniation. (balkanvets.com)
It has been proposed that the volume mismatch between the CCF and brain parenchyma in CKCS can be explained by impaired occipital bone development and the consequent reduction in CCF volume [5], [16], [21]. (journals.plos.org)