The structure of this enzyme was elucidated by isolating clones from a bovine brain complementary DNA library through the use of oligonucleotide probes derived from partial amino acid sequence. (science.sciencemag.org)
In the second technique, the presence of the beta A and beta S alleles is determined by restriction endonuclease digestion of an end - labeled oligonucleotide probe hybridized in solution to the amplified beta - globin sequences. (science.sciencemag.org)
Oligonucleotide probe selection and synthesis — The 1,178 genes comprising the Falk Center for Molecular Therapeutics (FCMT) Rat CNS microarray were compiled from currently available NCBI / EMBL / TIGR rat sequence databases and commercially available central nervous system (CNS) microarrays (Affymetrix, Santa Clara, CA) and provided representation from greater than 90 % of the major gene ontological categories [47]. (molvis.org)