Blocking of CD40L - mediated signaling represents a validated therapeutic strategy for treatment of auto - immune disorders and for preventing organ transplant rejection. (emulatebio.com)
Research on antimetabolites of nucleic acid purines led to drugs for the treatment of acute leukemia (6 - mercaptopurine and thioguanine), gout and hyperuricemia (allopurinol), and herpesvirus infections (acyclovir), and for the prevention of organ transplant rejection (azathioprine). (science.sciencemag.org)
Researchers are even working to develop tests for breast cancer and organ transplant rejection based on the bouquet of a patient's breath. (discovermagazine.com)