Felice notes, however, that in humans «BCL11A is expressed in other blood cell types,» which means that silencing it with treatments could lead to complications not seen in the current mouse study. (sciencemag.org)
Created with other blood cells in the bone marrow, they interfere with activation and proliferation of T cells, the immune system's attack cells. (sciencedaily.com)
Patients with Diamond - Blackfan anemia (DBA)-- an inherited disorder which disrupts the development of red cells in affected patients, but which does not affect the development of other blood cell types — offer researchers a particularly useful model for the study of these proteins. (stemcellsportal.com)