Here's the scientific description: «In this process, the capsaicin receptor (TRPV1) is sensitized by phosphatidylinositol -4,5-bisphosphate (PIP2) hydrolysis following phospholipase C activation.» (fieryfoodscentral.com)
This, in turn, is actually a lipid kinase and it phosphorylates lipids on the plasma membrane, making a new or synthesizing a new phosphate or a lipid phosphatidylinositol lipid called PIP - 3. (abcam.com)
PTEN can also reduce the levels of another similar molecule known as phosphatidylinositol -3,4-bisphosphate (PI (3,4) P2). (sciencedaily.com)