«Yingchun has developed methods to analyze both low and high abundant phosphotyrosine proteins from the pseudopodia,» says Klemke. (scripps.edu)
In cells transformed by viral Src, or some other oncoproteins, the amount of phosphotyrosine shot up 10-fold compared to normal cells. (the-scientist.com)
On the next slide I show you basically the key domain that's involved in this signaling interaction, so when the insulin receptor is phosphorylated, in order to recruit adaptors such as IRS - 1, it uses an important domain called the PTP domain, or phosphotyrosine containing peptides that can actually mediate this interaction, and lead to the interaction of these various molecules within the pathway. (abcam.com)