Specifically, maternally - inherited DNA methylation marks are important for normal placentation as they specify cellular properties such as adhesiveness and invasive character, as well as determining the correct balance of cell types needed in the placenta.» (sciencedaily.com)
It is connected with a low placentation, that is threat of premature labor because of an uterus tone. (infobaby.org)
Given the significant morbidities with multiple cesareans however, including surgical morbidity and abnormal placentation in future pregnancies, it is important to consider the possibility that for women with more than two prior cesareans VBAC may be associated with less morbidity, particularly in women with a high likelihood of success. (believemidwiferyservices.com)