The team designed the reaction system so that the product of CHA reaction has G - quadruplex structures, which is suitable to generate fluorescence. (sciencedaily.com)
He studies DNA and RNA quadruplexes, nucleic acid structures that were first visualized via confocal microscopy in fixed, dead cells. (sciencemag.org)
Using multiphoton microscopy, he could confirm that quadruplexes exist in living cells, indicating they likely have some function there. (sciencemag.org)