As for manganese in your well water, your best bet is to use a high quality filtering system using activated carbon. (articles.mercola.com)
Patterns of population splits and migration events were analyzed using TreeMix (82) and the intersection of SNPs passing quality filters for the ancient specimens, all modern horses, and the domestic donkey (when included). (pnas.org)
Filter Type 2: List Quality Filtering Many spam lists contain a large number of bogus addresses and therefore spammers «bounce» a lot of mails. (lawyercasting.com)