Consequently, G6PD deficiency may cause the destruction of RBCs leading to a condition known as hemolytic anemia in which the body can not compensate for the destroyed cells... (cags.org.ae)
For example, loss of Vitamin C creating gene accompanied rise of specific protective elements in the body, for instance type of GLUT receptors in RBCs as much as its somatin switch that regulates preference for glucose or C, and that is not present in any species not having dysfunctional gene. (perfecthealthdiet.com)
However, chronic rapamycin treatment was previously shown to increase rbc counts in young animals (i.e., apart from any aging - related changes)(39). (jci.org)