Heng Li's brilliant short read alignment tool finally went legit with a publication in Genome Research that came online this month. (massgenomics.org)
Few short read aligners can handle the throughput of Illumina data and allow for gaps in read alignments, because speed and gapped alignment are at odds with one another. (massgenomics.org)
Two papers by Langmead and team, Ultrafast and memory - efficient alignment of short DNA sequences to the human genome and Fast gapped - read alignment with Bowtie 2, have been cited in more than 12,000 scientific studies since 2009. (rdmag.com)