The award recognizes his work on the molecular regulation of lipid signaling complexes. (asbmb.org)
In this context, we have identified microcompartmentation of signaling complexes in the plasma membrane and in endosomes as important determinants for receptor dynamics and signaling activity. (biologie.uni-osnabrueck.de)
Control of T cell signaling occurs through both positive and negative regulation, as well as through the actions of molecular scaffolds that contribute to the formation of signaling complexes. (science.sciencemag.org)