Phenotypic screening of small molecule libraries using iPSC - based models to identify novel drug candidates and disease mechanisms. (dresden-ipp.de)
To test this hypothesis, Dr. Rubin said the next step will be to initiate a high throughput small molecule library screen in SMN - deficient motor neurons. (smafoundation.org)
Once the Vanderbilt small molecule library has been screened for potential modulators of the Y4 receptor, I will use the results to design efficient and accurate descriptors that can be used with artificial neural networks to predict activity at the Y4 receptor based on a small molecule's structural properties. (meilerlab.org)