She added that some of the fasting studies had very small numbers of subjects and needed to be replicated with many more participants. (healthcentral.com)
A statement should be included in all biomarker papers describing how overfitting (training models on large numbers of variables measured on small numbers of subjects) and other forms of bias were avoided. (sciencemag.org)
Most published studies entailed small number of subjects; well - designed studies with larger sample sizes are needed to ascertain how this test can reduce clinical diagnostic uncertainty or impact treatment planning. (aetna.com)