High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. (sens.org)
Stronger support for inflammation as a factor in PD comes from work in animal models of PD, which shows that drugs that inhibit pro-inflammatory responses by targeting the cytokine TNF can prevent degeneration of substantia nigra neurons. (lji.org)
are found in substantia nigra neurons of PD patients. (parkinson.org)