If you notice that your dog's energy has decreased, he seems ill, or he's exhibiting any of the general symptoms described above, please contact your veterinary immediately. (aspca.org)
Most of those adverse symptoms you describe don't sound like they're from Advantage, from what I understand. (fleascience.com)
The problem scale consists of 20 symptoms describing emotional, hyperactivity, conduct and peer problems. (link.springer.com)