But the new findings «are the first clear evidence for a molecular and cellular mechanism of synaptic loss in schizophrenia,» said Jonathan Sebat, chief of the Beyster Center for Molecular Genomics of Neuropsychiatric Diseases at the University of California, San Diego, who was not involved in the study. (scientificamerican.com)
The scientists also attempted to correlate all these minor synaptic losses with the subjects» level of dementia. (sciencedaily.com)
More recently, his lab started studying the genetic basis of human brain evolution as well as the signaling pathways underlying synaptic loss during early stages of Alzheimer's Disease progression. (polleuxlab.com)