Complementary DNA and genomic clones were isolated and sequenced corresponding to rat and human synaptophysin (p38), a major integral membrane protein of synaptic vesicles. (science.sciencemag.org)
The structure of synaptophysin suggests that the protein may function as a channel in the synaptic vesicle membrane, with the carboxyl terminus serving as a binding site for cellular factors. (science.sciencemag.org)
The rise in C3 protein level correlated with decreases in synaptic puncta and synaptophysin densities and synaptic protein, neuron loss, and reduced synaptic plasticity. (jax.org)