Phrases with «synthetic lethality»

Synthetic lethality refers to a concept where two genetic changes or mutations, which individually do not cause harm, become deadly when combined. It means that when two specific alterations occur together, they generate a lethal or harmful effect. This concept is often used in cancer research to discover new ways to target and treat tumors. Full definition

synthetic lethality

Sentences with «synthetic lethality»

Series A investors include 5AM Ventures, Canaan Partners, Celgene, WuXi Healthcare Ventures, Novartis Institute of Biomedical Research, and Alexandria Real Estate Small molecule programs with focus on synthetic lethality and... (ideayabio.com)
IDEAYA is pioneering the next generation of biomarker - enabled synthetic lethality therapies for genetically defined patient populations and advancing an immuno - oncology pipeline targeting immuno - metabolism and innate immunity. (ideayabio.com)
3) Unni A *, †, Lockwood WW *, †, Zejnullahu K, Lee - Lin S, Varmus H (2015) Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma. (bccrc.ca)
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Phrases with «synthetic lethality»

Sentences with «synthetic lethality»

See also