The main underlying cause is atherosclerosis, where fat accumulates in the blood vessel walls in the so - called plaques. (sciencedaily.com)
The body uses glucose accumulated in the blood, then the glycogen from the liver and muscles to their full capacity and once they are depleted, it begins to use fat as a source of energy. (fitnessandpower.com)
When the liver is damaged toxic substances normally removed by the liver accumulate in the blood and impair the function of brain cells. (safarivet.com)