It would cross the blood - brain barrier more efficiently, and thus in principle would require a smaller dose to achieve therapeutic effects in the brain. (sciencedaily.com)
With our proprietary technology, we are developing novel medicines designed to achieve therapeutic effects specifically at the source of disease to deliver new solutions for patients. (smafoundation.org)
«To achieve therapeutic effects in the brain, AAVs sometimes have to be given in high doses, which raises the possibility of dose - dependent toxicity,» said first author Blake Albright, a graduate research assistant at UNC. (sciencedaily.com)